Treatment Of Depression – Tenil Fri, 14 Jan 2022 23:36:53 +0000 en-US hourly 1 Treatment Of Depression – Tenil 32 32 Howard Solomon, 94, dies; His commercial success had a personal connection Fri, 14 Jan 2022 23:13:39 +0000

“Forest Pharmaceuticals deliberately chose to pursue corporate profits at the expense of its obligations to the FDA and the American public,” Carmen Ortiz, the US attorney from Massachusetts, said when the settlement was announced.

The company denied the allegations. In a statement at the time, Mr Solomon said: ‘We remain committed to ensuring that we operate in full compliance with all laws and regulations.

In 2011, Forest Labs won a proxy contest against activist shareholder Carl C. Icahn, who argued that the company had, among other things, lost billions of dollars in shareholder value over the previous decade. Mr. Icahn continued to sue Forest Labs with a second proxy fight in 2012, which ended with the election of one of his nominees to the company’s board.

In a letter to Mr. Icahn during that fight, Mr. Solomon wrote: “Your speech so far has shown a striking lack of strategic ideas. Instead, it was filled with savage and baseless accusations, innuendoes and distortions of facts.

Yet, at some point, Mr. Solomon contacted Mr. Icahn, and they had a series of dinner parties.

“We became friends,” Mr. Icahn said in a phone interview. “I thought he was a nice gentleman, a courteous guy.” He added: “I didn’t necessarily agree with the way he ran the business, but he was a nice guy who was delighted with the result. He made a lot of money.”

In 2013, Mr. Solomon announced his retirement as chief executive and was replaced by Brent Saunders, an executive friend of Mr. Icahn. Then, in early 2014, Actavis (now Allergan) paid $25 billion to acquire Forest Labs. Mr. Solomon, still chairman, left after the acquisition and formed a family investment company with his youngest son, David, who had been an executive at Forest Labs.

Besides his sons, Mr. Solomon is survived by his wife, Sarah Billinghurst Solomon, former assistant general manager of artistic affairs at the Metropolitan Opera, and five grandchildren. His first wife, Carolyn (Bower) Solomon, died in 1991.

rTMS may have potential to improve memory function in veterans with cognitive impairment Thu, 13 Jan 2022 03:14:00 +0000

Current treatments for Alzheimer’s disease are of limited effectiveness and do not halt disease progression and associated cognitive decline. A recent study, published in the Alzheimer’s Disease Journal, showed that a new treatment, repetitive transcranial magnetic stimulation (rTMS), may have the potential to improve memory function in veterans with cognitive impairment due to Alzheimer’s disease.

rTMS has already been approved by the FDA for the treatment of patients with treatment-resistant depression. Recent studies have also shown that rTMS can improve cognition. Under the direction of the Director and Co-Director of the Mental Illness Research Teaching and Clinical Center (MIRECC), Drs. Jerome Yesavage and J. Kaci Fairchild, a team of researchers from VA Palo Alto, conducted a pilot study to investigate the effect of rTMS on cognitive impairment in veterans with multiple medical comorbidities. Study participants completed 20 rTMS treatment sessions over a period of approximately 4 weeks.

The study protocol is similar to that used for the treatment of depression. Measures of these veterans’ cognitive function (including memory, language, fluency, and executive function) were acquired at baseline, at the end of treatment, and 4 months after the last rTMS session. The research team found that the study protocol was well tolerated. Thirty-two veterans with cognitive impairment likely due to early Alzheimer’s disease were enrolled, 29 completed the treatment phase of the study, and 26 (13 in the active rTMS group, 13 in the sham rTMS group) have completed all phases of the study and have been assessed.

Analysis of the study results suggested that the patients in the sham group showed an expected slight decline in memory tests during the study, while the active treatment group showed a slight improvement at 4 months of post-treatment follow-up. However, the active rTMS group also demonstrated a trend of decreased fluency at the end of treatment and at 4-month follow-up.

Conclusion: Pilot results show that rTMS is generally safe in this population of older veterans with cognitive impairment and multiple comorbidities, and that there was a suggestion of cognitive benefit for veterans receiving active treatment. Given the small sample size, these effects need to be confirmed by larger studies.

Abu Dhabi Public Psychiatric Clinics Offer New Nasal Spray to Treat Depression in Adults Tue, 11 Jan 2022 05:31:31 +0000

Abu Dhabi Health Services Company (Seha) offers Esketamine nasal spray for the treatment and management of severe depression in adults.
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Abu Dhabi: Depression patients in Abu Dhabi can now benefit from a new treatment that helps manage severe forms of mental illness.

Public health provider Abu Dhabi Health Services Company (Seha) has announced that it now offers Esketamine nasal spray for the treatment and management of severe depression in adults. The spray is recommended for patients who have tried other modalities of antidepressant treatment without benefit.

New treatment

Esketamine targets new receptors in the brain than those traditionally treated with antidepressants. It has shown a good safety profile and tolerability in patients, and the Seha facilities with psychiatric clinics have therefore introduced the new therapy for patients with treatment-resistant depression.

“At Seha, our goal has always been to provide our patients with the highest standards of treatment. Our team of highly experienced psychiatrists and psychologists strive to provide a holistic and integrated treatment modality, tailored to each patient. Mental health and its treatment differs from patient to patient, which is why we are happy to add another method of treatment to our services, giving us more bandwidth to explore treatment solutions as suitable as possible for every patient, ”said Dr Nahida Niaz Ahmed. , consultant psychiatrist and president of the Seha Behavioral Health Council /

Patient experiences

A number of patients have recently shared their experiences after receiving the treatment, highlighting how esketamine has made their recovery easier.

A 30-year-old man, who has suffered from major depressive disorder for six years, was prescribed esketamine after trying several types of drugs, antidepressants and even shock therapy (ECT), which did not all failed to relieve him of his depression. A month after his doctor started taking the nasal spray, he began to notice a positive impact on his outlook and lifestyle. Now he exercises daily, is comfortable interacting socially, and has become much more motivated to find a job and support his family.

Suicidal tendencies

Another 20-year-old woman who was diagnosed with severe depression with suicidal tendencies had previously had no relief with other medications. The nasal spray helped improve her condition and significantly reduce her thoughts of suicide.

Another young man returned to school after receiving treatment. Previously, he had isolated himself in his room and had stopped studying for more than three years, which in turn had damaged his physical and mental health. The patient said he has gradually been able to deal with negative thoughts and is now replacing them with goals and ambitions for a better future.

Vernon-based Doseology has established itself in the US market with several products – Vernon News Sat, 08 Jan 2022 23:00:00 +0000

A Vernon-based business that uses “magic mushroom” elements for mental health has started in the United States.

Doseology has introduced seven new adaptogenic mushroom products to the US market.

The diversified life sciences company that develops mushroom-based health and wellness solutions will also launch the product line into the Canadian market in the first quarter of 2022.

Doseology’s website says its mission is to “restore mental health by establishing psychedelic-assisted therapy clinics, building an intellectual property library through research on psychedelic compounds,” and developing and selling products. made from brand name functional mushrooms.

He says these can be used for the treatment of depression, PTSD and other mental health disorders.

“Significant research has shown the positive effects of adaptogens in reducing stress, resisting mental fatigue and improving attention span,” a company statement said.

“The Doseology line combines adaptogens such as ginger, turmeric, yerba mate and several species of mushrooms, with proven functional mushrooms such as lion’s mane, reishi, shiitake, maitake, royal sun, turkey tail and others. These blended formulations provide enhanced health and wellness benefits over single ingredient products. “

The new product line is aimed at the functional mushroom market, which is expected to reach $ 572 billion worldwide by 2028.

The products in the new Doseology line are aimed at different market segments, including mood and depression, attention and focus, sleep, recovery and anxiety.

In preparation for the Canadian launch, Doseology received six natural product number licenses from Health Canada.

The company is currently exploring Canadian distribution channels, which should include

“After several months of product development, testing and regulatory approvals, we are pleased to finally launch our products in the US market and soon in Canada. By incorporating the nutrient-rich fruiting bodies of functional fungi and natural health-promoting adaptogens, our products have been designed to optimize the user experience, reflecting our commitment to providing high-quality, natural solutions to improve health. physical and mental, ”said Daniel Vice, CEO and Director of Doseology.

A central part of the company’s mission is to develop and deliver psychedelic treatments to restore mental health. Once the regulatory framework is established, Doseology’s product line will form the basis of psilocybin-based therapies, creating a whole new market and realizing the company’s vision of better mental health and well-being. for millions of people around the world.

Doseology has completed its application to Health Canada to become an “authorized distributor” under the Controlled Drugs and Substances Act (Canada), which would allow the production of psychedelic compounds, including psilocybin and psilocin.

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Alembic Pharma Gets Interim USFDA Approval for Depression Drug Fri, 07 Jan 2022 19:22:00 +0000

Alembic Pharmaceuticals Ltd announced on Friday that it had received interim approval from the US health regulator for its generic vortioxetine tablets indicated for the treatment of major depressive disorder.

The interim approval granted by the United States Food & Drug Administration (USFDA) for its Abbreviated New Drug Application (ANDA) for vortioxetine 5 mg, 10 mg, 15 mg and 20 mg tablets, indicated the company in a press release.

These are therapeutically equivalent to the Reference Drug Product (RLD) 5 mg, 10 mg, 15 mg and 20 mg Trintellix tablets from Takeda Pharmaceuticals, USA, Inc, he added.

Citing data from IQVIA, the company said that these vortioxetine tablets have an estimated market size of $ 1,249 million for a twelve-month period ending in September 2021.

Alembic, however, said he is currently in litigation with H Lundbeck in the Federal Circuit Court of Appeals and that the product launch will depend on the outcome of the litigation.

“Our ANDA may not be listed for some uses due to unexpired RLD exclusives for such uses,” the company said.

(Only the title and image of this report may have been reworked by Business Standard staff; the rest of the content is automatically generated from a syndicated feed.)

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New national survey shows encouraging signs of reducing stigma surrounding farmer mental health Wed, 05 Jan 2022 15:28:49 +0000

Farmers and rural dwellers are more comfortable talking about stress and mental health issues with others, and the stigma of seeking help or treatment has decreased in rural and farming communities. but remains a factor, according to one new research poll of the American Farm Bureau Federation.

AFBF surveyed rural adults and farmer / farm workers to measure changes and trends in stigma, personal experiences with mental health, awareness of mental health resource information and the comfort of talking about mental health with others. The results of the survey were compared to previous AFBF surveys conducted in 2019 and 2020 which focused on the mental health of farmers and the impacts of the COVID-19 pandemic on the mental health of farmers, respectively.

“Farm Bureau has encouraged conversations to help reduce the stigma surrounding stress and the mental health of farmers through our Farm State of Mind campaign,” said Zippy Duvall, AFBF President. “This poll shows we are making a difference, but we all still have work to do. It is up to each of us to continue to look after our family, friends and neighbors and let them know that they are not alone when they feel the increasing stress that comes with the daily activities of farming and farming. breeding.

Morning Consult conducted the survey on behalf of the AFBF in December 2021 with a national sample of 2,000 rural adults. The main findings include:

  • The stigma associated with seeking help or treatment for mental health has diminished but remains a factor, particularly in agriculture. Over the past year, there has been a decrease in the number of rural adults reporting that their friends / acquaintances (-4%) and members of their local community (-9%) stigmatized asking for help. help or treatment for mental health. But a majority of rural adults (59%) say there is at least some stigma around stress and mental health in the farming community, including 63% of farmers / farm workers.
  • Farmers / farm workers are more comfortable talking about stress and mental health with friends, family and doctors than they were in 2019. Four in five rural adults (83%) and 92% of farmers / farm workers say they would be comfortable talking about solutions with a friend or family member facing stress or a mental health issue, and the percentage of farmers / farm workers who say they would be comfortable talking to friends and family has increased by 22% since April 2019.
  • A majority of rural adults (52%) and farmer / farm workers (61%) experience more stress and mental health issues than a year ago, and seek care due to stress increased. Young rural adults are more likely than older rural adults to say they experience more stress and mental health problems than a year ago, and they are more likely than older rural adults to say that they are experiencing more mental health problems. ‘they personally sought treatment from a mental health professional.

A slide set with additional details of the full survey results is available here.

The AFBF will present two events focused on farmer mental health at the 103rd AFBF Convention in Atlanta, Georgia: a panel discussion with representatives from the Farm Bureau on Sunday, January 9 at 10:45 a.m. EST, and a workshop QPR Mental Health Training Course hosted by AgriSafe that equips farmers and farm families with the skills to recognize and respond to mental health crises using the Ask, Persuade and Refer approach, Monday January 10 at 2:00 p.m. EST.

If you or someone you know is in emotional pain or has concerns about their mental health, visit the Farm State of Mind website at for information on the case helplines. crisis, treatment locators, tips to help someone with emotional pain, how to start a conversation. and resources to manage stress, anxiety or depression.


Mike tomko
Director, Communications
(202) 406-3642

Ray atkinson
Director, Communications
(202) 406-3717

Back to the press room

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Worsening symptoms of depression linked to shorter survival in lung cancer patients Mon, 03 Jan 2022 17:06:34 +0000

January 03, 2022

3 minutes to read

Source / Disclosures

Disclosures: Andersen does not report any relevant financial disclosure. Please see the study for relevant financial information from all other authors.

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According to the results of a study published in Psychosomatic medicine.

The study is the first to examine how the trajectory of depressive symptoms affects the survival of patients with lung cancer, according to a press release from Ohio State University.

Quote from Barbara L. Anderson, PhD.

“Data show that post-diagnostic trajectories of psychological symptoms predict the risk of premature mortality from advanced non-small cell lung cancer, even controlling for the survival benefits of immune and targeted therapies.” Barbara L. Andersen, PhD, eminent college professor in the Department of Psychology at Ohio State University, Healio said. “Substantial evidence points to the need for psychological therapies to treat the common comorbidities of stress, depression and anxiety with advanced NSCLC.”

Andersen added that improving the psychological state of patients can help prolong quality of life and, potentially, OS. Meanwhile, if depressive symptoms are left untreated, patients may have suboptimal understanding of their disease and treatment, impaired decision making or commitment to treatment, lower tolerance symptoms and adverse events of treatment, and low motivation to maintain functional status, she said.

“Lung patients have received so little attention in psychosocial research. They are in the midst of a therapeutic revolution, but the significant problems of depression remain, ”said Andersen. “We are trying to send an alarm on their psychological needs.”

The analysis included 157 patients (mean age, 63.76 years; standard deviation, 10.74 years; 56.7% male; 93% white) with stage non-small cell lung cancer. IV at the Ohio State University Comprehensive Cancer Center from June 2017 to October 2019.

Andersen and colleagues collected completed questionnaires on validated measures of depressive and anxiety symptoms at diagnosis and assessed patients regularly – monthly for up to 8 months, then bimonthly until death or 24 months (average completion rate 80%).

About 28% of the patients had moderate levels of depression at the time of diagnosis, while 8% had moderate to severe levels and the rest had lower levels. Additionally, 6% had moderate anxiety levels and 18% had moderate to severe levels.

The researchers used joint statistical models for the simultaneous modeling of longitudinal (psychological) and time-to-event (survival) processes. They also considered age, race, employment status, income level, and smoking – other factors that can influence survival – in their analyzes.

The median follow-up was 8.7 months (range: 1.1-31.4).

The results showed that symptoms of depression and anxiety decreased significantly with time from diagnosis, but the trajectory of depressive symptoms appeared to be significantly associated with cancer survival after adjusting for covariates (HR per unit increase in Patient Health Questionnaire score = 1.09; 95% CI: 1.03-1.15). Additionally, the researchers reported marginally significant anxiety in the unadjusted model, but not in the fitted model.

According to a press release, patients without depression or with only mild levels 3 months after diagnosis had a more than 50% chance of surviving 15 months, compared to more than 30% for those with moderate to severe levels of depression.

“Depression is a toxic psychosocial and behavioral symptom relevant to predicting overall mortality, regardless of the presence or absence of chronic disease,” Andersen told Healio.

Patients who received newer treatments that dramatically improved survival for many lung cancer patients also saw their lives shortened if they suffered from worsening depression, the press release said.

“Even as impressive new treatments come online, their effectiveness may be limited for patients who also have depression,” Andersen said in the release. “These data are new in suggesting that depression continues as a major limiting factor even when the best therapies available to us for lung cancer are used.”

She added that the study results were “incredibly compelling evidence” of the need to help these patients, beyond diagnosis, with depressive symptoms.

“Our research shows that psychological interventions performed during this period – the first few months after diagnosis – have shown robust biobehavioral effects and a reduced risk of recurrence in others. [patients with cancer]”Andersen told Healio.” Our intention is to conduct a randomized trial with these patients to test the effectiveness of treatment for depression in improving survival and reducing the risk of premature death. “

The references:

Andersen BL, et al. J Clin Oncol. 2021; doi: 10.1200 / JCO.2004.06.030.
The worsening of depression reduces the survival of patients with lung cancer. Posted October 12, 2021. Accessed December 15, 2021.

For more information:

Barbara L. Andersen, PhD, can be contacted at the Department of Psychology, Ohio State University, 1835 Neil Ave., Columbus, OH 43210-1222; email:

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BMC strings in TB survivors to counsel patients, see drop-out rates reduced Sat, 01 Jan 2022 21:46:57 +0000 In 2018, Seema Kunchikorne contracted multidrug-resistant pulmonary tuberculosis (MDR-TB). From 65 kg, her weight fell to 45 kg and she sank into depression. Her husband took her to her mother’s house and she was eventually admitted to Sewri TB Hospital.

“I was on oxygen therapy and the doctors had also given up hope. I didn’t give up because of my son, who I hadn’t seen for two years. I pushed myself to eat. In three months in the hospital I gained 8 kg and in 2020 I was declared tuberculosis free, ”Kunchikorne said.

Now divorced, the Dharavi resident is one of 24 TB survivors, which the Brihanmumbai Municipal Corporation (BMC), in a one-of-a-kind initiative, hired to counsel other patients to ensure better adherence. to the treatment regimen. Launched in November 2021, the initiative has already yielded an encouraging response by decreasing dropout rates despite the Covid-19 outbreak in Wave 3, officials said.

The volunteers are called “Saksham Sathi” and their job is to ensure better adherence to DOTS treatment, curb dropouts, bring back failers and increase the rate of recovery.

Kunchikorne said her recovery journey made her aware of the unspoken issues facing TB patients, which often affect their mental health and treatment regimen.

“This is a unique initiative taken in India. Tuberculosis survivors are role models for active patients. By talking to them, patients have the belief that they can also be cured of the disease, which can be cured with the appropriate drugs, ”said Dr Pranita Tipre, head of tuberculosis control in Mumbai.

In addition to smart tablets, tuberculosis survivors receive Rs 10,000 per month as part of the initiative, as well as Rs 500 to recharge their devices.

Dr Tipre said that previously many patients refused to give out their bank details for the Rs 500 monthly incentive provided for their nutrition. “These TB survivors are teaching patients the importance of nutrition in their recovery. Thanks to this, we were able to collect the bank details of many patients, ”she added.

A study – assessing the prevalence of depression and its associated factors in tuberculosis patients in Ernakulam district, Kerala – found that one sixth of tuberculosis patients suffer from depression, with the prevalence being higher in patients with tuberculosis. multidrug-resistant tuberculosis.

A person with tuberculosis can develop depression due to several factors such as the long duration of treatment, social stigma and lack of family support, officials said.

Speaking to The Indian Express, another ‘Saksham Sathi’, Yashwant Amrut Marathe, 23, said TB survivors can communicate better with patients because they have faced a similar type of stigma and discrimination .

“To patients who worry about their career gaps due to illness, I share with them my story, how I got over it and how well I am now in my life. We are like their friends who can really relate to them, without giving them false sympathy, ”said the resident of Santa Cruz who contracted tuberculosis in 2017.

Currently, survivors, trained by the civic body, advise patients over the phone.

“Soon we will start community engagement where, alongside the group counseling of patients, we will also involve their loved ones,” said Dr Tipre.

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How to deal with seasonal depression Thu, 30 Dec 2021 23:36:00 +0000

PINE BELT, Mississippi (WDAM) – As the holiday season draws to a close, seasonal depression is at its peak according to medical leaders.

The holidays can be a joyous time for family and friends, but they can also add additional stress. Caroline Smith, director of addiction services at Pine Grove, explained why people may feel sad during this time.

“What also contributes to the holiday blues is that this holiday season comes when the days are the shortest in the calendar year. And, due to the time change, it gets darker earlier, so people have less opportunity to be exposed to natural sunlight. And SAD, seasonal affective disorder. A lot of people suffer from it and it happens most often in January and February, ”Smith said.

Smith also says people can have unrealistic expectations of wanting the perfect vacation, which can eventually make you feel overwhelmed. This is one of the many reasons why it’s important to get back to your pre-vacation routine.

“There’s going to be a rebound effect where the brain tries to reach homeostasis, it doesn’t just go there, it often goes to the other side and we have these symptoms of depression and blues,” Smith said. .

South Central Behavioral Health therapist Rhonda Smith explains that there are symptoms people should watch out for.

“The symptoms of seasonal depression are just a change in your behavior. You want to withdraw from others, you sleep too much or not enough. You no longer have a feeling of hopelessness and helplessness. So every time you have a change in mood you might want to take a look and see what’s causing it, ”Smith said.

Smith also suggests taking advantage of as much natural sunlight as possible, while making sure you take your daily vitamins such as vitamin C.

“If you feel like you need help, ask for therapy, ask for medication if you need it. If it is something as bad as having thoughts of suicide, always seek help, ”Smith said.

Both experts say being mindful of your emotions is the key to a successful vacation transition.

Copyright 2021 WDAM. All rights reserved.

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What does the scientific evidence say about the paleo diet? Wed, 29 Dec 2021 14:22:25 +0000

The promotion of certain diets as a means of improving overall health is very common. In recent years, a food model called the Paleolithic regime – also known as the Paleo Diet, for short – has taken the health and wellness world by storm.

Despite the popularity of the paleo diet, many researchers and health professionals argue that it is not necessarily the best diet for improving overall health. In fact, some believe it can be harmful.

In this article on Honest Nutrition, we dig a little deeper into the research on the paleo diet to discover its potential health benefits. We also discuss the risks that can arise while following a paleo diet.

A paleo diet, also known as the Stone Age diet or the caveman diet, is a diet that aims to reflect how hunter-gatherers ate thousands of years ago. years.

People who follow a paleo diet eat large amounts of meat, fruits, vegetables, nuts, and seeds, but limit legumes, dairy products, and grains.

Foods and beverages that a person on a paleo diet frequently consumes include:

  • meat, with an emphasis on meat from wild game or grass-fed animals
  • fish
  • eggs
  • the water
  • herbal tea
  • fruit
  • herbs and spices
  • nuts
  • seeds
  • healthy oils, like walnut or olive oil

Foods that a person on a paleo diet will often avoid include:

  • dairy products
  • refined sugar
  • salt
  • legumes, which include beans, peanuts, and peas
  • artificial ingredients
  • processed foods
  • soft drink
  • grains, including rice, wheat, and oats
  • potatoes

One of the most common misconceptions about the Paleo diet is that our ancestors mainly survived on a meat-based diet.

As we learn more about the Paleolithic Age, we find that those who lived there ate a plant-based diet, with only one guess. 3% of their diet derived from food of animal origin.

Supporters of the Paleo diet believe that the shift from a hunter-gatherer style diet to an agricultural diet has increased the global prevalence of chronic diseases, including heart disease, obesity and diabetes.

They believe that the human body is not genetically equipped to consume the modern foods that agricultural practices have introduced. As a result, they believe that our overall health will improve by following a diet similar to that of our ancestors.

The claimed benefits of a paleo diet include:

  • improved cholesterol
  • reduced blood pressure
  • improved blood sugar control
  • reduced waist circumference and weight loss
  • improved satiety
  • improved gut health
  • reduction in all-cause mortality

Switching from a western diet high in processed foods high in sodium to a paleo diet will result in the inclusion of more fresh fruits and vegetables, which can undoubtedly be beneficial for overall health.

Many people also report improvements in inflammation, focus, and sleep. They also report weight loss, which is likely due to increased consumption of whole foods while removing major food groups.

While the paleo diet has the potential to be healthy, is it necessary to restrict grains, legumes, and dairy to see the health benefits?

Let’s discuss how the paleo diet compares scientifically.

Several breakthroughs in science and research have allowed us to further explore the potential benefits of the paleo diet to determine whether it should become a diet that medical professionals regularly recommend.

A 2015 review reviewed four randomized controlled trials with 159 participants who exhibited one or more of the five components of metabolic syndrome.

Researchers found that Paleolithic nutrition resulted in greater short-term improvements in the following areas compared to the control diet:

  • waist size
  • triglyceride levels
  • arterial pressure
  • high density lipoprotein (HDL) or “good” cholesterol levels
  • fasting blood sugar

A study published in the Nutrition Journal evaluated several randomized controlled trials to establish a relationship between the Paleolithic diet and chronic disease prevention and control and anthropometric measures.

The study found an average weight loss of 3.52 kilograms as well as a decrease in waist circumference and body mass index (BMI) in those who ate a Paleolithic diet compared to those who ate other commonly recommended diets.

The researchers behind this study suggest that following a paleo diet may reduce the risk of chronic diseases, as excess body weight is one of the main risk factors for their development.

Is The Paleo Diet Better Than Other Diets?

A study published in the Nutrition Journal aimed to study the associations of the Paleolithic diet and the Mediterranean diet with all-cause and specific mortality.

The study found that those who followed a Paleo or Mediterranean diet had reduced all-cause mortality, lower oxidative stress, and mortality from heart disease and cancer.

A meta-analysis of 2020 reviewed four studies to compare the Paleo diet with the Mediterranean diet, the diabetes diet, and another diet recommended by the Dutch Board of Health. Researchers looked at the effects of these diets on glucose and insulin homeostasis in people with impaired glucose metabolism.

They found that those who followed the paleo diet did not experience significant improvements in fasting blood sugar, insulin levels, or HbA1c levels compared to those who followed the other types of diet. The study authors conclude that the paleo diet is not superior to other nutritious diets in people with impaired glucose metabolism.

In addition, a study published in the journal Nutrition in January 2020 reviewed the effectiveness of different diets, including the paleo diet and intermittent fasting.

Its authors found that to date, there is no specific diet that can effectively support weight loss in all individuals. They concluded that the best diet for weight loss is a negative energy balance while focusing on food quality.

Removing certain food groups can improve certain health markers and lead to weight loss, but it can also lead to nutrient deficiencies and increase the risk of long-term health consequences.

For example, a paleo diet restricts dairy products, which are rich in calcium and vitamin D, two nutrients essential for bone health. A deficiency in these nutrients can lead to osteoporosis and bone fractures.

This diet also removes beans and legumes. Beans are a great source of minerals, fiber, and plant protein. They can also help lower cholesterol and promote satiety, the feeling of being full after a meal.

Plus, many people who follow a paleo diet claim that it promotes gut health, but new research says otherwise.

Some studies suggest that those who follow a paleo diet have a different gut microbiota and higher levels of trimethylamine N-oxide (TMAO), a compound linked to cardiovascular disease.

This research supports current dietary recommendations to include foods high in fiber and whole grains to maintain cardiovascular function and gut health.

Those who take a modern approach to the paleo diet often use it as an excuse for overeating meat. Eating more than the recommended servings of meat, especially red meat, on a daily basis can lead to chronic disease.

Excessive protein intake from any animal source increases the body’s production of insulin-like growth factor 1 (IGF-1). High levels of IGF-1 and high intake of dietary protein can lead to increased risk cancer, diabetes and overall mortality.

The paleo diet is also generally very high in saturated fat. According to American Cardiovascular Association (AHA), a person should limit their intake of saturated fat to no more than 13 grams per day to avoid high cholesterol and heart disease. Eating too much red meat can also damage the kidneys.

A person should aim to eat a maximum of 12 to 18 ounces (about 350 to 500 grams) of red meat each week. People with heart problems should limit their consumption of red meat to less than this amount.

According to an article in Australian family doctor, the paleo diet is overestimated and under-studied. The author calls for longer-term studies to continue to assess the benefits and risks of this diet.

However, the paleo diet model can be difficult to fully adhere to in the long term, making it difficult to formulate more conclusive recommendations.

Unless a person has a health problem that requires them to restrict a specific food group, there is no scientific evidence to show that the paleo diet is superior to other well-known diets, such as the Mediterranean diet.

Diets high in fruits, vegetables, lean protein, and whole grains allow for more variety, are more sustainable, and are scientifically proven to provide health benefits.

It is possible to get all the necessary nutrients from the foods allowed in the Paleo diet, but it can be difficult. For example, people will need to focus on getting calcium from non-dairy sources, such as dark green leafy vegetables.

Anyone who plans to change their diet should consult a doctor or dietitian first.

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